The Wound Management Innovation Cooperative Research Centre (WMI CRC) was established in Australia on 1 July 2010 and its first 3.5 years of operations has led to social, clinical and technological innovations that are assisting in the delivery of improved wound care. This centre, the largest wound research initiative globally to date, is underpinned by $108 million in cash and in-kind contributions provided over 8 years by the Australian federal government and 22 research organisations, industry partners and end-user participants. The goal of the WMI CRC is to improve wound healing and quality of life for people with wounds, and provide cost-effective wound care that lessens the burden on the health system. This is being achieved by: improving our understanding of the mechanisms of wound healing; developing novel wound products (diagnostics, prognostics, therapies and dressings) and processes (clinical care pathways, prevention strategies, risk assessment tools); and translating best practice wound care into clinical settings. The research is conducted within 3 end-user driven research programs: Enabling Technologies; Tools & Therapies; and Clinical Application, and represents the collective multidisciplinary expertise of ~sixty equivalent full time researchers including cell biologists, materials scientists, clinicians, economists, information technologists, health service providers and industry. This presentation will describe research outcomes and translation highlights from the WMI CRC to date, with a particular focus on outcomes from the Enabling Technologies and Clinical Application research programs.